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Susumu Tanimura Selected Research

Proteasome Endopeptidase Complex (Proteasome)

1/2021Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteins during mitophagy.
1/2019Cleaved PGAM5 is released from mitochondria depending on proteasome-mediated rupture of the outer mitochondrial membrane during mitophagy.

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Susumu Tanimura Research Topics

Disease

17Neoplasms (Cancer)
03/2017 - 05/2003
2Hypertension (High Blood Pressure)
01/2021 - 01/2016
2Rupture
01/2021 - 01/2019
2Obesity
12/2016 - 04/2016
2Cardiovascular Diseases (Cardiovascular Disease)
01/2016 - 09/2012
2Fibrosarcoma
07/2011 - 05/2005
2Cysts
04/2009 - 06/2006
1Autoimmune Diseases (Autoimmune Disease)
06/2022
1Familial Mediterranean Fever (Periodic Disease)
06/2022
1Mitochondrial Diseases (Mitochondrial Disease)
01/2021
1Human Influenza (Influenza)
01/2021
1Glioma (Gliomas)
03/2017
1Leukemia
03/2017
1Inflammation (Inflammations)
12/2016
1Type 2 Diabetes Mellitus (MODY)
04/2016
1Insulin Resistance
04/2016
1Hyperglycemia
04/2016
1Hyperlipidemias (Hyperlipidemia)
04/2016
1Hypertrophy
04/2016
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
12/2013
1Carcinoma (Carcinomatosis)
07/2011
1Breast Neoplasms (Breast Cancer)
07/2011
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2010
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2010
1Pneumococcal Pneumonia
07/2006
1Pneumonia (Pneumonitis)
07/2006
1Disease Progression
06/2006
1Polycystic Kidney Diseases (Polycystic Kidney Disease)
06/2006
1Neoplasm Metastasis (Metastasis)
05/2005

Drug/Important Bio-Agent (IBA)

7Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
04/2016 - 05/2003
7Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
04/2016 - 04/2009
62- (2- chloro- 4- iodophenylamino)- N- cyclopropylmethoxy- 3,4- difluorobenzamideIBA
04/2016 - 05/2003
4Histone Deacetylase InhibitorsIBA
04/2013 - 02/2008
3Pharmaceutical PreparationsIBA
06/2022 - 07/2004
3SaltsIBA
01/2021 - 09/2012
3MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA
03/2012 - 05/2003
2Proteins (Proteins, Gene)FDA Link
06/2022 - 05/2003
2Proteasome Endopeptidase Complex (Proteasome)IBA
01/2021 - 01/2019
2Tubulin ModulatorsIBA
07/2011 - 08/2007
2DNA (Deoxyribonucleic Acid)IBA
02/2008 - 02/2006
2Matrix Metalloproteinases (MMPs)IBA
05/2005 - 05/2003
1Monoclonal AntibodiesIBA
06/2022
1Single-Domain AntibodiesIBA
06/2022
1Granzymes (Granzyme)IBA
01/2021
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
01/2021
1alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA
03/2017
1WP1066IBA
03/2017
1ruxolitinibIBA
03/2017
1InflammasomesIBA
03/2017
1Cysteine Proteases (Cysteine Protease)IBA
12/2016
1Leptin ReceptorsIBA
04/2016
1Phosphotransferases (Kinase)IBA
04/2016
1AdipokinesIBA
04/2016
1Glucose (Dextrose)FDA LinkGeneric
04/2016
1mirdametinibIBA
04/2016
1Antihypertensive Agents (Antihypertensives)IBA
01/2016
1NicotineFDA Link
12/2013
1Chewing Gum (Chewing Gums)IBA
12/2013
1AZD 6244IBA
04/2013
1Histone Deacetylases (Histone Deacetylase)IBA
04/2013
1entinostat (MS 275)IBA
04/2013
1Apoptosis Regulatory ProteinsIBA
03/2012
1NCX 4040IBA
07/2011
11- (4- chlorobenzoyl)- 5- methoxy- 2- 1H- indole- 3- acetic acid 3-(nitrooxymethyl)phenyl esterIBA
07/2011
1TubulinIBA
07/2011
1Phenol (Carbolic Acid)FDA Link
07/2011
1Vincristine (Oncovin)FDA LinkGeneric
07/2011
1aniline (aniline hydrobromide)IBA
07/2011
1BI D1870IBA
05/2011
1Antineoplastic Agents (Antineoplastics)IBA
01/2011
1soblidotin (TZT 1027)IBA
02/2010
1Vinorelbine (Navelbine)FDA LinkGeneric
02/2010
1ErbB Receptors (EGF Receptor)IBA
01/2010
1Imatinib Mesylate (Gleevec)FDA Link
01/2010
1Gefitinib (Iressa)FDA Link
01/2010
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2010
1Cytostatic AgentsIBA
01/2010
1Bromodeoxyuridine (BrdU)IBA
04/2009
1Protein Kinases (Protein Kinase)IBA
04/2009
1DeoxyuridineIBA
04/2009
1Histones (Histone)IBA
02/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2008
1Heat-Shock Proteins (Heat-Shock Protein)IBA
12/2007
1CathepsinsIBA
12/2007
1MacrolidesIBA
07/2006
1Proliferating Cell Nuclear Antigen (PCNA)IBA
06/2006
1Mitogen-Activated Protein KinasesIBA
06/2006
1p38 Mitogen-Activated Protein KinasesIBA
06/2006
1JNK Mitogen-Activated Protein KinasesIBA
06/2006
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2006
1Doxorubicin (Adriamycin)FDA LinkGeneric
02/2006
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
02/2006
1TeaIBA
05/2005
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
05/2005
1Hydrolyzable TanninsIBA
05/2005
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
05/2005
1beta-d-glucoseIBA
05/2005
11,2,4- tri- O- galloyl- 3,6- hexahydroxydiphenoylglucoseIBA
05/2005

Therapy/Procedure

2Therapeutics
06/2022 - 01/2011
1Oral Administration
04/2016